Colonies have the most combined stats (if you are trying to reach the highest cs possible) and the most troops of any T5 building. The last point is important as it will allow you to have more hits per full unload (but you'd need longer to fully regenerate), up to 27 hits instead 24 per unload.
If you are hesitating because of the defensive stats of the Hatchery, don't worry. As troops go down, the defense of any troop building will go down too. For wars, towers will be the way to go defense-wise, as those stats don't depend on your troop levels, they are static.
If you prefer to look a bit more offensive as a hitter, there is no real downside of mixing colonies and hatcheries (most prefer sticking to colonies though).